Prerequisite: (None) This course covered the principle of biology, earth space. The main concepts are classification, characteristic, needs and relations among living organisms, cells, tissues, organs, systems, human body and its health, plants, genetic engineering, cloning, genetic map, genetically modified foods. Also it covered the universe component, sun, moon, geopolitical activities, and broad cashing. Teaching methods of these concept will include constructivism, cooperative learning, concept maps, projects and using wet and dry lab.